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Prices About us How does it work Laboratory Contacts
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Apixmed Prism — an innovative next-generation genetic analytics platform
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Immunity, Infections and Autoimmune Conditions | DNA Test
Illustration of a Y-shaped antibody on a blue background with a green “with DNA kit” badge — the Immunity, Infections and Autoimmune Conditions genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Immunity, Infections and Autoimmune Conditions genetic test: Systemic autoimmune conditions, Organ-specific autoimmune conditions, Inflammatory bowel disease, Immune-mediated skin and joint conditions, Bacterial and urinary infections, Viral infections and severity of illness, Other infections and debated phenotypes, Immune and inflammatory biomarkers — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 41 complex traits, 16 individual genetic variants — the Immunity, Infections and Autoimmune Conditions genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of a Y-shaped antibody on a blue background with a green “with DNA kit” badge — the Immunity, Infections and Autoimmune Conditions genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Immunity, Infections and Autoimmune Conditions genetic test: Systemic autoimmune conditions, Organ-specific autoimmune conditions, Inflammatory bowel disease, Immune-mediated skin and joint conditions, Bacterial and urinary infections, Viral infections and severity of illness, Other infections and debated phenotypes, Immune and inflammatory biomarkers — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 41 complex traits, 16 individual genetic variants — the Immunity, Infections and Autoimmune Conditions genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Immunity, Infections and Autoimmune Conditions | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT!

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Immunity, Infections and Autoimmune Conditions genetic test covers 57 markers across eight areas of immune system function, including 41 complex markers and 16 individual genetic variants in 15 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 57 markers and genetic variants in plain language, with an interpretation of the results:

    • 41 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 16 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Immunity, Infections and Autoimmune Conditions genetic test covers eight areas, within which it analyzes 41 complex markers and 16 individual genetic variants in 15 genes: from systemic and organ-specific autoimmune conditions to infections and immune biomarkers. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements an immunological work-up and laboratory tests rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

41 markers across eight areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Systemic autoimmune conditions: autoimmune disease (general marker), systemic autoimmune connective tissue disease, systemic lupus erythematosus, rheumatoid arthritis, systemic sclerosis, Sjögren's syndrome, Behçet's disease, sarcoidosis, antiphospholipid syndrome

  • Organ-specific autoimmune conditions: type 1 diabetes, autoimmune thyroid disease, Graves' disease, celiac disease, multiple sclerosis, myasthenia gravis, biliary cholangitis, sclerosing cholangitis

  • Inflammatory bowel disease: Crohn's disease, ulcerative colitis

  • Immune-mediated skin and joint conditions: psoriasis, psoriatic arthritis, atopic dermatitis, ankylosing spondylitis

  • Bacterial and urinary infections: tuberculosis, pneumonia, meningitis, urinary tract infections, Clostridioides difficile infection

  • Viral infections and severity of illness: hepatitis B, hepatitis C, shingles, HIV infection and AIDS progression, mumps, severe COVID-19

  • Other infections and debated phenotypes: Lyme disease

  • Immune and inflammatory biomarkers: neutrophil count, monocyte count, eosinophil count, basophil count, total serum immunoglobulin E (IgE), C-reactive protein

Individual genetic variants with mechanistic links

16 genetic variants in 15 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • PTPN22, STAT4, CTLA4 and TNFAIP3: associated with systemic autoimmune conditions

  • IL7R and IL2RA: associated with multiple sclerosis and autoimmune conditions

  • NOD2 and ATG16L1: variants of these genes are among the best-studied associations with Crohn's disease, four variants

  • IL23R and TRAF3IP2: associated with psoriasis and inflammatory bowel disease

  • FCGR2A: associated with ulcerative colitis

  • TLR4: an innate immunity receptor, associated with the inflammatory response to infection

  • OAS1, DPP9 and LZTFL1: associated with the severity of COVID-19

Who the Apixmed Prism Immunity, Infections and Autoimmune Conditions DNA Test is for

  • Family history of autoimmune diseases: specific genetic context for a conversation with a rheumatologist or immunologist.

  • Chronic inflammatory symptoms: additional context for a conversation with your doctor, not a self-diagnosis.

  • Interest in prevention: specific topics for laboratory monitoring instead of guesswork.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Immunity, Infections and Autoimmune Conditions test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace immunological testing, antibody testing or endoscopy. Clinical decisions are made by a specialist, taking into account your history, symptoms, age, medication and laboratory data.

Frequently Asked Questions

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How does a genetic immunity test differ from immunological testing?
Immunological and laboratory tests (C-reactive protein, IgE, specific antibodies) show the state of the immune system here and now. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. Immunological testing shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Does carrying NOD2 mean I will definitely get Crohn's disease?
No. The NOD2 variants increase relative genetic predisposition to Crohn's disease, but most carriers never develop the condition: its development depends on additional factors, including the state of the microbiome and the immune system. Diagnosis is established from endoscopy, biopsy and a gastroenterologist's examination, not from the genotype.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
Does an elevated genetic predisposition to severe COVID-19 mean the illness will definitely be severe?
No. The result describes relative genetic predisposition, not a prognosis for a specific case of illness. The severity of an infection depends on many additional factors: age, coexisting conditions, vaccination status and the state of the immune system at the time of infection.
How reliable is a genetic immunity test?

The reliability of a genetic immunity test has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic immunity test diagnose an autoimmune disease?
No, the test does not establish diagnoses and does not rule out conditions, including rheumatoid arthritis, multiple sclerosis or Crohn's disease. If you have symptoms, see the relevant doctor: only they can carry out diagnosis and treatment.
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Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.