







IMPORTANT!
THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.
The Apixmed Prism Allergies and Intolerances genetic test covers 28 markers across four areas of allergic predisposition and food intolerances, including 17 complex markers and 11 individual genetic variants in 9 genes.
A DNA kit for collecting your saliva sample yourself is already included in the price of the test.
Genotyping of the sample in an accredited laboratory.
A report explaining 28 markers and genetic variants in plain language, with an interpretation of the results:
17 polygenic (complex) traits with an explanation of your individual result and what it means;
11 individual genetic variants with an explanation of their possible biological significance.
Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.
Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.
The option of a consultation with an Apixmed Prism specialist based on your report results.
Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.
Data protection in line with ISO 27001, GDPR and HIPAA standards.
The Allergies and Intolerances genetic test covers four areas, within which it analyzes 17 complex markers and 11 individual genetic variants in 9 genes: from general allergic predisposition to respiratory allergies, food intolerances and skin reactions. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements allergological work-up and laboratory tests rather than replacing them.
DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.
17 markers across four areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.
General allergic predisposition and biomarkers: allergic sensitization, total serum immunoglobulin E (IgE), food allergy, eosinophil count
Respiratory and inhalant allergies: allergic rhinitis, asthma, sensitization to animal allergens, cat allergy, dog allergy
Food intolerances and immune-mediated reactions: lactase persistence, fructose metabolism and absorption, celiac disease, peanut allergy, egg allergy
Skin and contact allergies: atopic dermatitis, allergic contact dermatitis, angioedema
11 genetic variants in 9 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.
IL13 and IL4R: associated with IgE levels and atopic dermatitis, three variants
TSLP: associated with asthma and allergic predisposition
FCER1A: the IgE receptor, associated with total IgE levels
MCM6: a gene whose variant regulates the activity of the lactase gene LCT, associated with lactase persistence
SERPINB: a gene cluster associated with food allergy
AOC1 and HNMT: histamine-metabolizing enzymes, associated with how quickly it is broken down, four variants
Discomfort after certain foods: genetic context on lactose, fructose or histamine for a conversation with your doctor or dietitian.
Family history of allergic conditions: specific topics to discuss with an allergist.
Chronic respiratory symptoms: additional context for a conversation with your doctor, not a self-diagnosis.
When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.
The Allergies and Intolerances test is not a diagnosis and does not replace consultation with a doctor.
The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm an allergy or intolerance and do not determine treatment. The test does not replace allergy skin testing, IgE testing or celiac serology. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.