Apixmed
PRISM
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Prices About us How does it work Laboratory Contacts
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Apixmed Prism — an innovative next-generation genetic analytics platform
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Dental and Oral Health | DNA Test
Illustration of a tooth on a blue background with a green “with DNA kit” badge — the Dental and Oral Health genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Dental and Oral Health genetic test: Teeth: development, cavities and enamel, Gums, periodontium and oral microbiome, Jaw, bite and orofacial pain, Oral and pharyngeal cancers, Nutrients related to dental and gum tissue, Systemic links to oral health — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 29 complex traits, 6 individual genetic variants — the Dental and Oral Health genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of a tooth on a blue background with a green “with DNA kit” badge — the Dental and Oral Health genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Dental and Oral Health genetic test: Teeth: development, cavities and enamel, Gums, periodontium and oral microbiome, Jaw, bite and orofacial pain, Oral and pharyngeal cancers, Nutrients related to dental and gum tissue, Systemic links to oral health — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 29 complex traits, 6 individual genetic variants — the Dental and Oral Health genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Dental and Oral Health | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT! 

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Dental and Oral Health genetic test covers 35 markers across six areas of tooth and gum health and related nutrients, including 29 complex markers and 6 individual genetic variants in 6 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 35 markers and genetic variants in plain language, with an interpretation of the results:

    • 29 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 6 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Dental and Oral Health genetic test covers six areas, within which it analyzes 29 complex markers and 6 individual genetic variants in 6 genes: from tooth development and cavities to gum health, bite and nutrients related to dental tissue. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements a dental examination rather than replacing it.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

29 markers across six areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Teeth: development, cavities and enamel: cavities, enamel hypoplasia, number of teeth in adulthood, timing of baby tooth eruption, number of baby teeth

  • Gums, periodontium and oral microbiome: gum disease, periodontitis, a combined genetic score for periodontitis and tooth mobility (MTAG), average clinical attachment loss, bleeding gums, composition of the oral microbiome

  • Jaw, bite and orofacial pain: temporomandibular joint pain disorder, chronic pain, migraine

  • Oral and pharyngeal cancers: oral cancer, oropharyngeal cancer, pharyngeal cancer

  • Nutrients related to dental and gum tissue: vitamin D (25(OH)D), phylloquinone (vitamin K1), vitamin C, folate (vitamin B9), calcium, phosphorus, magnesium, zinc, iron

  • Systemic links to oral health: bone density, rheumatoid arthritis, Sjögren's syndrome

Individual genetic variants with mechanistic links

6 genetic variants in 6 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • KCNJ2 and CACNB2: associated with the timing of baby tooth eruption

  • IL1A and IL1B: associated with the inflammatory response of periodontal tissue

  • MMP3: associated with connective tissue breakdown in periodontitis

  • FUT2: secretor status, associated with the composition of the oral microbiome

Who the Apixmed Prism Dental and Oral Health DNA Test is for

  • A family predisposition to periodontitis: specific genetic context for a conversation with a periodontist.

  • Frequent cavity problems: additional context on nutrients for tooth enamel.

  • Interest in prevention: specific topics for routine dental check-ups.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Dental and Oral Health test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace a dental exam, X-rays or professional cleaning. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and exam results.

Frequently Asked Questions

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How does a genetic dental test differ from a dental exam?
A dental exam and X-rays show the actual state of your teeth and gums here and now. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. A dental exam shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
Does an elevated genetic predisposition to oral cancer mean I will definitely develop it?
No. The test analyzes polygenic associations, not variants of high-penetrance hereditary syndromes. An elevated genetic predisposition is not a prognosis of disease: decisions about check-ups and next steps are made by a doctor.
How reliable is a genetic dental test?

The reliability of a genetic dental test has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic dental test diagnose periodontitis or cavities?
No, the test does not establish diagnoses and does not rule out conditions, including periodontitis or cavities. If you have symptoms, see a dentist: only they can carry out diagnosis and treatment.
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Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.