Apixmed
PRISM
Prices About us How does it work Laboratory Contacts
Prices About us How does it work Laboratory Contacts
EN
keyboard_arrow_down
UA
check
EN
check
RU
check
person
0
Prices About us How does it work Laboratory Contacts
Prices About us How does it work Laboratory Contacts
Untitled
Apixmed Prism — an innovative next-generation genetic analytics platform
Read more arrow_outward Untitled
Home keyboard_arrow_right Prices keyboard_arrow_right
Glucose and Metabolic Syndrome | DNA Test
Illustration of a glucose meter on a blue background with a green “with DNA kit” badge — the Glucose and Metabolic Syndrome genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Glucose and Metabolic Syndrome genetic test: Glycemic biomarkers, Insulin secretion and action, Spectrum of carbohydrate metabolism disorders, Overall fat mass, Body composition (fat and muscle mass), Adipokines, Appetite regulation signals, Metabolic conditions and urate, Diabetic complications — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 36 complex traits, 15 individual genetic variants — the Glucose and Metabolic Syndrome genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of a glucose meter on a blue background with a green “with DNA kit” badge — the Glucose and Metabolic Syndrome genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Glucose and Metabolic Syndrome genetic test: Glycemic biomarkers, Insulin secretion and action, Spectrum of carbohydrate metabolism disorders, Overall fat mass, Body composition (fat and muscle mass), Adipokines, Appetite regulation signals, Metabolic conditions and urate, Diabetic complications — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 36 complex traits, 15 individual genetic variants — the Glucose and Metabolic Syndrome genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Glucose and Metabolic Syndrome | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT!

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Glucose and Metabolic Syndrome genetic test covers 51 markers across nine areas of carbohydrate and energy metabolism, including 36 complex markers and 15 individual genetic variants in 15 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 51 markers and genetic variants in plain language, with an interpretation of the results:

    • 36 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 15 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

View a sample report arrow_outward
Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Glucose and Metabolic Syndrome genetic test covers nine areas, within which it analyzes 36 complex markers and 15 individual genetic variants in 15 genes: from glycemic biomarkers and insulin action to body composition, appetite regulation and metabolic conditions. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure blood glucose or insulin levels — instead it examines the stable genetic context that complements laboratory tests rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

36 markers across nine areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Glycemic biomarkers: fasting glucose, glycated hemoglobin, glucagon

  • Insulin secretion and action: insulin, proinsulin, HOMA-B (beta-cell function), insulin sensitivity

  • Spectrum of carbohydrate metabolism disorders: prediabetes, type 1 diabetes, type 2 diabetes

  • Overall fat mass: body mass index (BMI), body fat percentage, overweight, obesity

  • Body composition (fat and muscle mass): waist circumference, hip circumference, visceral fat, liver fat fraction, appendicular lean mass, body-to-muscle mass ratio

  • Adipokines: adiponectin, leptin, resistin

  • Appetite regulation signals: appetite-regulating hormones, ghrelin, the leptin receptor, soluble leptin receptor, peptide YY, agouti-related peptide

  • Metabolic conditions and urate: metabolic syndrome, metabolic dysfunction-associated steatotic liver disease (MASLD, also known as fatty liver disease), uric acid, gout

  • Diabetic complications: diabetic neuropathy, diabetic nephropathy, diabetic retinopathy

Individual genetic variants with mechanistic links

15 genetic variants in 15 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • SLC30A8, PPARG and KCNJ11: associated with type 2 diabetes

  • MTNR1B: the melatonin receptor, associated with glucose levels

  • TCF7L2: a variant of this gene is one of the most reproducible associations with type 2 diabetes

  • GCKR: regulation of glucose and lipid metabolism in the liver

  • ADRB3 and PLIN1: associated with lipolysis (the breakdown of fat tissue)

  • UCP1 and UCP2: associated with thermogenesis and energy metabolism

  • FTO: regulation of appetite and body weight, associated with body mass index

  • MC4R: associated with appetite regulation and BMI

  • PNPLA3 and TM6SF2: associated with liver fat accumulation

  • ABCG2: associated with uric acid levels

Who the Apixmed Prism Glucose and Metabolic Syndrome DNA Test is for

  • Family history of type 2 diabetes or obesity: specific genetic context for a conversation with an endocrinologist, not a reason for conclusions on your own.

  • Interest in weight management: additional context on energy metabolism and appetite alongside professional nutritional assessment.

  • Existing risk factors for metabolic syndrome: specific topics for laboratory monitoring instead of guesswork.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Glucose and Metabolic Syndrome test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace glucose, glycated hemoglobin or other laboratory measurements. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.

Frequently Asked Questions

Contact us arrow_outward
How does a genetic diabetes test differ from a glucose or glycated hemoglobin test?
A laboratory test measures the level here and now, and it is affected by diet, weight, physical activity and current health status. A genetic test does not measure the level: it describes statistical associations between DNA variants and markers established in population studies. A glucose and glycated hemoglobin test shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Does an elevated genetic predisposition to diabetes mean I will definitely develop it?
No. The result describes relative genetic predisposition, not a prognosis of disease. The development of type 2 diabetes depends on many additional factors: weight, physical activity, diet, age and coexisting conditions. Type 1 diabetes has a different, largely autoimmune nature, and the variants in this test are not the primary tool for assessing predisposition to it.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
What does the TCF7L2 variant mean?
TCF7L2 is a gene whose variant is one of the most reproducible associations with type 2 diabetes found in scientific research: it is linked to insulin secretion by the pancreas. On its own, the variant does not establish a diagnosis and does not indicate a specific glucose level: that requires laboratory tests and a doctor's examination.
Наскільки надійний генетичний тест на діабет?

The reliability of a genetic diabetes test has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic diabetes test diagnose diabetes or metabolic syndrome?
No, the test does not establish diagnoses and does not rule out conditions, including diabetes, obesity or metabolic syndrome. If you have symptoms or abnormal laboratory results, see a doctor: only they can carry out diagnosis and treatment.
Contact us arrow_outward

Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.