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Prices About us How does it work Laboratory Contacts
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Apixmed Prism — an innovative next-generation genetic analytics platform
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Musculoskeletal System, Injury and Recovery | DNA Test
Illustration of a spine and pelvis on a blue background with a green “with DNA kit” badge — the Musculoskeletal System, Injury and Recovery genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Musculoskeletal System, Injury and Recovery genetic test: Muscle mass and function, Bone density and fracture risk, Joint health, Spine and back health, Tendons, ligaments and tunnel syndromes — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 22 complex traits, 15 individual genetic variants — the Musculoskeletal System, Injury and Recovery genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of a spine and pelvis on a blue background with a green “with DNA kit” badge — the Musculoskeletal System, Injury and Recovery genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Musculoskeletal System, Injury and Recovery genetic test: Muscle mass and function, Bone density and fracture risk, Joint health, Spine and back health, Tendons, ligaments and tunnel syndromes — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 22 complex traits, 15 individual genetic variants — the Musculoskeletal System, Injury and Recovery genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Musculoskeletal System, Injury and Recovery | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT! 

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Musculoskeletal System, Injury and Recovery genetic test covers 37 markers across five areas of the musculoskeletal system, including 22 complex markers and 15 individual genetic variants in 8 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 37 markers and genetic variants in plain language, with an interpretation of the results:

    • 22 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 15 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Musculoskeletal System, Injury and Recovery genetic test covers five areas, within which it analyzes 22 complex markers and 15 individual genetic variants in 8 genes: from muscle mass to bone density, and the health of joints, the spine, tendons and ligaments. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements an orthopedic examination rather than replacing it.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

22 markers across five areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Muscle mass and function: muscle strength, muscle volume, appendicular lean mass, thigh muscle fat infiltration, muscle mass loss, sarcopenia

  • Bone density and fracture risk: bone mineral density, osteoporosis, fractures

  • Joint health: osteoarthritis, joint pain, joint stiffness, knee pain, adhesive capsulitis of the shoulder

  • Spine and back health: lumbar intervertebral disc degeneration, lumbar disc herniation, lumbar spinal stenosis

  • Tendons, ligaments and tunnel syndromes: tendinopathy, Achilles tendon injury, ankle injury, Dupuytren's contracture, carpal tunnel syndrome

Individual genetic variants with mechanistic links

15 genetic variants in 8 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • WNT16 and LRP5: associated with bone density, three variants

  • VDR: the vitamin D receptor, three variants associated with bone mineral density

  • GDF5: associated with osteoarthritis and joint health, two variants

  • TGFA: associated with joint health

  • COL5A1 and COL1A1: associated with the structure of tendons and ligaments, three variants

  • TNC: associated with predisposition to tendon injury, three variants

Who the Apixmed Prism Musculoskeletal System, Injury and Recovery DNA Test is for

  • Regular physical exercise: additional genetic context on predisposition to tendon injury, without predicting outcomes.

  • Family history of osteoporosis: specific genetic context for a conversation with your doctor about prevention.

  • Age 50+ and joint care: specific topics for routine orthopedic check-ups.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Musculoskeletal System, Injury and Recovery test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace bone densitometry, X-rays, MRI or an orthopedic examination. Clinical decisions are made by a specialist, taking into account your history, symptoms, age, medication and test results.

Frequently Asked Questions

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How does a genetic test for joints and bones differ from bone densitometry or X-rays?
Bone densitometry and X-rays show the actual state of bones and joints here and now. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. Bone densitometry shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Does an elevated genetic predisposition to osteoporosis mean I will definitely have fractures?
No. The result describes relative genetic predisposition, not a fracture prognosis. Bone density depends on many factors: diet, physical activity, hormonal status and age. Regular bone densitometry remains the primary monitoring tool regardless of genotype.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
How reliable is a genetic test for joints and bones?

The reliability of a genetic test for joints and bones has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic test for joints and bones diagnose osteoporosis or osteoarthritis?
No, the test does not establish diagnoses and does not rule out conditions, including osteoporosis or osteoarthritis. If you have symptoms, see an orthopedist or rheumatologist: only they can carry out diagnosis and treatment.
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Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.