How to collect a saliva sample for a DNA testhome: step-by-step instructions
Most people who order a genetic test for the first time imagine the process as something like a trip to the lab: a line, a needle, blood. In fact, everything is simpler than it seems. Collecting a sample forThe DNA test takes a few minutes and is performed at home – without any medical manipulation.
This guide will guide you through the entire process, from receiving your DNA kit to sending your sample.
If you are interested in how a DNA test differs from a regular blood test and why DNA can be obtained from saliva, – DNA test and blood test: what's the difference?
Why saliva and not blood?
DNA is found in every cell of the body, including the cells of the oral mucosa, which are constantly exposed to saliva. The quality of the genetic material is no different from that obtained from blood. The result of the analysis is the same.
That's why modern DTC genetic tests use saliva: it's convenient, painless, and doesn't require the involvement of medical personnel. The entire process takes place in the comfort of your own home, at a time that's convenient for you.
What's in the DNA kit?
Before you start, check the package. The Apixmed Prism kit includes:
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Gloves
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Saliva collection kit consisting of three elements:
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Test tube (A)with buffer solution and protective seal
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Funnel (B)for collecting saliva
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Lid (C)for hermetically sealing the test tube
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Envelope for sending a sample – located under the lodgement at the bottom of the box
All components must be dry. If in doubt, contactto the support service before the start of the collection (+380 68 992 55 55,support@apixmed.com.ua, Instagram: @apixmed.prism.ua).
Preparation: one hour before saliva sample collection
The quality of the sample directly depends on preparation. An hour before collecting saliva, it is necessary toto refrainfrom:
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food
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any drinks
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teeth cleaning
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using mouthwash
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smoking
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chewing gum
Why is this important? Food, drink, and hygiene residues can get into the sample and reduce sample quality. The laboratory checks the quality of each sample before analysis – and if the sample does not meet the requirements, it will have to be collected again.
One hour of preparation instead of re-assembly is a simple agreement with yourself.
Step-by-step instructions for collecting a saliva sample for DNA analysis
The entire process consists of four steps. It usually takes between 5 and 15 minutes, depending on how actively saliva is produced.
Step 1. Preparation
Put on the protective gloves provided. This reduces the risk of contaminating the sample with foreign genetic material from your hands. Then firmly secure the funnel (B) onto the top of the tube (A) – it should sit flat and without gaps.
Step 2. Saliva collection
Hold the tube with the funnel upright. Bring it to your mouth and slowly fill it with saliva until the liquid (not foam) reaches the fill line on the tube.
Two important points: make sure that the liquid, not the foam, gets into the tube, and take your time. If the saliva is produced slowly, that's normal, just wait. The process can take several minutes.
Step 3. Closing the tube
Holding the tube vertically, carefully remove the funnel. Then screw the cap (C) tightly. As you screw it on, the protective seal is broken, allowing the saliva to mix with the buffer solution. This is exactly what should happen.
Step 4. Preparing for shipment
Invert the closed tube 10 times to ensure complete mixing of the saliva with the reagent and stabilize the sample for transport. Then place the tube in the envelope located under the lodgment at the bottom of the box.
Shipping details – method and address – will be in the letter you will receive by e-mail after ordering.
What happens after sending a saliva sample?
Once the saliva sample has arrived at the partner laboratory in the EU, a multi-step process begins:
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Sample quality check
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DNA isolation
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Analysis of over 600,000 genetic markers
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Data file generation
After that, Apixmed Prism interprets the results and generates a personal report with explanations and personalized recommendations tied specifically to your genetic profile.
The total turnaround time is up to 16 weeks from the moment the laboratory receives the sample.
Important: the sample is de-identified before it is sent to the laboratory. In the EU, it arrives under a barcode, without a name or personal data. The results are linked to your profile already on the Apixmed Prism side.
Frequently asked questions
Can I collect a sample when I have a cold or illness?
It is better to wait until you recover. During illness, the quality of DNA in saliva can decrease due to increased mucus and other impurities. If you have already collected a sample and only then become ill, send it, the laboratory will check the quality.
What if I accidentally ate less than an hour before the appointment?
Wait a little longer and collect the sample after a full hour. There is no need to start over from scratch.
How long does a sample remain viable after collection?
The buffer solution stabilizes the sample for transport. Send it as soon as possible after collection – ideally the same day or the next.
Where can I find an envelope for sending?
The envelope is located under the lodgment (removable stand) at the bottom of the DNA kit box.
Everything you need to know
Collecting a saliva sample is the easiest part of the entire process. An hour without food or drink, five minutes for collection, and the sample is ready to be sent. The laboratory and the Apixmed Prism algorithm take care of the rest.
If you haven't ordered a set yet → view available DNA tests Apixmed Prism
