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Prices About us How does it work Laboratory Contacts
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Apixmed Prism — an innovative next-generation genetic analytics platform
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Digestive System Health and Microbiome | DNA Test
Illustration of intestines on a blue background with a green “with DNA kit” badge — the Digestive System Health and Microbiome genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Digestive System Health and Microbiome genetic test: Esophagus and reflux conditions, Stomach and peptic conditions, Bowel motility and function, Inflammatory bowel disease, Immune-mediated and structural gut conditions, Microbiome, microbial exposure and gut barrier — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 22 complex traits, 4 individual genetic variants — the Digestive System Health and Microbiome genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of intestines on a blue background with a green “with DNA kit” badge — the Digestive System Health and Microbiome genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Digestive System Health and Microbiome genetic test: Esophagus and reflux conditions, Stomach and peptic conditions, Bowel motility and function, Inflammatory bowel disease, Immune-mediated and structural gut conditions, Microbiome, microbial exposure and gut barrier — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 22 complex traits, 4 individual genetic variants — the Digestive System Health and Microbiome genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Digestive System Health and Microbiome | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT! 

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Digestive System Health and Microbiome genetic test covers 26 markers across six areas of digestive system function, including 22 complex markers and 4 individual genetic variants in 4 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 26 markers and genetic variants in plain language, with an interpretation of the results:

    • 22 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 4 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Digestive System Health and Microbiome genetic test covers six areas, within which it analyzes 22 complex markers and 4 individual genetic variants in 4 genes: from the esophagus and stomach to bowel motility, inflammatory bowel conditions and the microbiome. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not diagnose any condition directly — instead it examines the stable genetic context that complements a gastroenterological examination rather than replacing it.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

22 markers across six areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Esophagus and reflux conditions: esophageal disease, gastroesophageal reflux disease, Barrett's esophagus, esophageal cancer

  • Stomach and peptic conditions: stomach disease, gastritis, peptic ulcer disease, stomach ulcer, duodenal ulcer, stomach polyp, nausea

  • Bowel motility and function: irritable bowel syndrome (IBS), stool frequency, constipation

  • Inflammatory bowel disease: Crohn's disease, ulcerative colitis

  • Immune-mediated and structural gut conditions: celiac disease, malabsorption syndrome, diverticular disease

  • Microbiome, microbial exposure and gut barrier: gut microbiome variability, gut permeability, Helicobacter pylori seropositivity

Individual genetic variants with mechanistic links

4 genetic variants in 4 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • MCM6: a gene whose variant regulates the activity of the lactase gene LCT, associated with lactase persistence — the ability to digest lactose in adulthood

  • NOD2: recognition of bacterial components in the gut; three variants are among the best-studied associations with Crohn's disease

  • FUT2: secretor status, associated with interaction with the gut microbiome

Who the Apixmed Prism Digestive System Health and Microbiome DNA Test is for

  • Discomfort after dairy products: genetic context on lactase persistence for a conversation with your doctor or dietitian.

  • Family history of inflammatory bowel disease or celiac disease: specific topics for a work-up instead of guesswork.

  • Chronic digestive symptoms: additional context for a conversation with a gastroenterologist, not a self-diagnosis.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Digestive System Health and Microbiome test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace endoscopy, stool tests or other gastroenterological investigations. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.

Frequently Asked Questions

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Does a genetic gut test mean I definitely can't digest lactose?
No. The test shows a genetic predisposition to lactase persistence — the ability to produce the lactase enzyme in adulthood. Actual tolerance of dairy products also depends on dose, the composition of the gut microbiome and coexisting gut conditions, so the final conclusion is made by a doctor or dietitian, not by the genotype alone.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Does carrying NOD2 variants mean I will definitely get Crohn's disease?
No. The NOD2 variants increase relative genetic predisposition to Crohn's disease, but most carriers never develop the condition: its development depends on additional factors, including the state of the microbiome and the immune system. Diagnosis is established from endoscopy, biopsy and a gastroenterologist's examination, not from the genotype.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
How does a genetic gut test differ from stool testing or endoscopy?
Endoscopy and laboratory stool testing show the state of the digestive system here and now. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. Endoscopy and stool testing show the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How reliable is a genetic gut test?

The reliability of a genetic gut test has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic gut test diagnose a bowel condition?
No, the test does not establish diagnoses and does not rule out conditions, including Crohn's disease, celiac disease or irritable bowel syndrome. If you have symptoms, see a gastroenterologist: only they can carry out diagnosis and treatment.
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Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.