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Prices About us How does it work Laboratory Contacts
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Apixmed Prism — an innovative next-generation genetic analytics platform
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Kidneys and Urinary Tract | DNA Test
Illustration of kidneys on a blue background with a green “with DNA kit” badge — the Kidneys and Urinary Tract genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Kidneys and Urinary Tract genetic test: Filtration and nitrogen metabolism, Electrolytes, minerals and urate, Glomerular and inflammatory conditions, Kidney and urinary tract diseases — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 23 complex traits, 6 individual genetic variants — the Kidneys and Urinary Tract genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of kidneys on a blue background with a green “with DNA kit” badge — the Kidneys and Urinary Tract genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Kidneys and Urinary Tract genetic test: Filtration and nitrogen metabolism, Electrolytes, minerals and urate, Glomerular and inflammatory conditions, Kidney and urinary tract diseases — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 23 complex traits, 6 individual genetic variants — the Kidneys and Urinary Tract genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Kidneys and Urinary Tract | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT! 

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Kidneys and Urinary Tract genetic test covers 29 markers across four areas of kidney and urinary tract function, including 23 complex markers and 6 individual genetic variants in 5 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 29 markers and genetic variants in plain language, with an interpretation of the results:

    • 23 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 6 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Kidneys and Urinary Tract genetic test covers four areas, within which it analyzes 23 complex markers and 6 individual genetic variants in 5 genes: from kidney filtration function to electrolyte balance, kidney stones and other conditions of the urinary tract. It assesses how your genetic profile and individual genetic variants are associated with relatively higher or lower values for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements blood and urine tests rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

23 markers across four areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Filtration and nitrogen metabolism: estimated glomerular filtration rate (eGFR), serum creatinine, cystatin C, serum urea, albuminuria, uromodulin

  • Electrolytes, minerals and urate: serum sodium, serum potassium, chloride, calcium, phosphorus, uric acid

  • Glomerular and inflammatory conditions: glomerulonephritis, IgA nephropathy, nephritis, nephropathy, nephrotic syndrome

  • Kidney and urinary tract diseases: chronic kidney disease, kidney failure, polycystic kidney disease, kidney stones, urinary tract infections, urinary frequency

Individual genetic variants with mechanistic links

6 genetic variants in 5 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • SHROOM3: associated with eGFR and kidney function

  • UMOD: uromodulin; two variants are among the best-studied associations with eGFR and predisposition to chronic kidney disease

  • CASR: the calcium-sensing receptor, associated with calcium levels

  • ABCG2: associated with uric acid levels

  • SLC2A9: a urate transporter, associated with uric acid levels

Who the Apixmed Prism Kidneys and Urinary Tract DNA Test is for

  • Family history of chronic kidney disease or kidney stones: specific genetic context for a conversation with a nephrologist.

  • Existing risk factors (blood pressure, diabetes, gout): additional context on kidney workload.

  • Interest in long-term prevention: specific topics for routine check-ups instead of guesswork.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Kidneys and Urinary Tract test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace blood and urine tests, ultrasound or other kidney investigations. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.

Frequently Asked Questions

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How does a genetic kidney test differ from blood and urine tests for kidney function?
Blood and urine tests (creatinine, eGFR, albuminuria) show the state of the kidneys here and now, and they are affected by hydration, diet, medication and current health. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. Blood and urine tests for kidney function show the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Does an elevated genetic predisposition mean I will definitely develop chronic kidney disease?
No. The result describes relative genetic predisposition, not a prognosis of disease. The development of chronic kidney disease depends on many additional factors: blood pressure, glucose levels, age and coexisting conditions. Decisions about further investigations are made by a doctor.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
What does the UMOD variant mean?
UMOD encodes uromodulin, a protein produced by the kidneys themselves. Its variants are among the most reproducible associations with glomerular filtration rate and predisposition to chronic kidney disease. On its own, the variant does not establish a diagnosis and does not indicate a specific level of kidney function: that requires laboratory tests and a doctor's examination.
How reliable is a genetic kidney test?

The reliability of a genetic kidney test has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic kidney test diagnose kidney disease?
No, the test does not establish diagnoses and does not rule out conditions, including chronic kidney disease, glomerulonephritis or kidney stones. If you have symptoms or abnormal laboratory results, see a doctor: only they can carry out diagnosis and treatment.
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Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.