Apixmed
PRISM
Prices About us How does it work Laboratory Contacts
Prices About us How does it work Laboratory Contacts
EN
keyboard_arrow_down
UA
check
EN
check
RU
check
person
0
Prices About us How does it work Laboratory Contacts
Prices About us How does it work Laboratory Contacts
Untitled
Apixmed Prism — an innovative next-generation genetic analytics platform
Read more arrow_outward Untitled
Home keyboard_arrow_right Prices keyboard_arrow_right
Longevity and Biological Aging | DNA Test
Illustration of a sprouting seedling on a blue background with a green “with DNA kit” badge — the Longevity and Biological Aging genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Longevity and Biological Aging genetic test: Lifespan, healthspan and integrated aging, Molecular and cellular aging, Physical vulnerability, mobility and resilience, Brain and cognitive aging, Sensory aging, Bone aging and fractures, Reproductive and visible markers of aging — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 35 complex traits, 18 individual genetic variants — the Longevity and Biological Aging genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of a sprouting seedling on a blue background with a green “with DNA kit” badge — the Longevity and Biological Aging genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Longevity and Biological Aging genetic test: Lifespan, healthspan and integrated aging, Molecular and cellular aging, Physical vulnerability, mobility and resilience, Brain and cognitive aging, Sensory aging, Bone aging and fractures, Reproductive and visible markers of aging — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 35 complex traits, 18 individual genetic variants — the Longevity and Biological Aging genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Longevity and Biological Aging | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT!

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Longevity and Biological Aging genetic test covers 53 markers across seven areas of aging and resilience, including 35 complex markers and 18 individual genetic variants in 19 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 53 markers and genetic variants in plain language, with an interpretation of the results:

    • 35 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 18 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

View a sample report arrow_outward
Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Longevity and Biological Aging genetic test covers seven areas, within which it analyzes 35 complex markers and 18 individual genetic variants in 19 genes: from healthspan and molecular aging to bone fragility, brain aging and sensory changes. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly and does not show your biological age — instead it examines the stable genetic context that complements clinical assessment and laboratory tests rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

35 markers across seven areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Lifespan, healthspan and integrated aging: exceptional longevity, healthspan, pace of aging

  • Molecular and cellular aging: telomere length, epigenetic age acceleration, the Klotho protein, catalase, superoxide dismutase activity, thioredoxin

  • Physical vulnerability, mobility and resilience: frailty index, muscle mass loss, sarcopenia, reduced grip strength in older age, usual walking pace, physical activity, orthostatic hypotension

  • Brain and cognitive aging: cognitive decline, episodic memory, short-term memory, processing speed, reaction time, dementia, Alzheimer's disease, frontotemporal dementia, dementia with Lewy bodies, Parkinson's disease

  • Sensory aging: cataracts, age-related macular degeneration, age-related hearing loss

  • Bone aging and fractures: bone mineral density, osteoporosis, fractures, hip fracture

  • Reproductive and visible markers of aging: skin aging, hair graying

Individual genetic variants with mechanistic links

18 genetic variants in 19 genes and loci. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • FOXO3: cellular stress resistance; a variant of this gene is one of the most reproducible associations with exceptional longevity

  • CDKN2B-AS1: a locus associated with cardiometabolic aging

  • CHRNA5: associated with nicotine dependence, one of the main modifiable factors in aging

  • TERC, TERT, RTEL1, POLD3 and STN1/OBFC1: associated with telomere length

  • KL-VS: a haplotype of the Klotho gene associated with longevity, inherited as a heterozygote advantage rather than additively

  • CAT, SOD2 and GPX1: antioxidant defense enzymes, associated with oxidative stress

  • SLC39A8, GDF5 and TGFA: associated with frailty and joint health in older age

  • CFH, ARMS2 and C3: associated with age-related macular degeneration

The APOE gene deserves a separate explanation. Its haplotype — the combination of the ε2, ε3 and ε4 variants — is associated with cholesterol levels and, separately, with relative genetic predisposition to cognitive aging and late-onset Alzheimer's disease. This is the best-studied genetic factor of its kind, but carrying the ε4 variant does not mean the disease will necessarily develop: penetrance is incomplete, and a large share of carriers never show clinical signs. Equally, not carrying this variant does not guarantee protection. Given the emotional weight of this information, discussing the decision to take this specific test with a doctor or genetic counselor is worth considering regardless of the result you receive.

Who the Apixmed Prism Longevity and Biological Aging DNA Test is for

  • Interest in long-term prevention: specific topics for planning regular check-ups as you age.

  • Family history of dementia or macular degeneration: specific genetic context for a conversation with a neurologist or ophthalmologist.

  • Active longevity: additional context on physical vulnerability and resilience for a conversation with your doctor.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Longevity and Biological Aging test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not show your biological age, do not predict lifespan and do not determine treatment. The test does not replace cognitive testing, vision and hearing exams, bone densitometry or consultation with a doctor. Clinical decisions are made by a specialist, taking into account your history, symptoms, age, medication and test results.

Frequently Asked Questions

Contact us arrow_outward
Does the APOE ε4 variant mean I will definitely get Alzheimer's disease?
No. The ε4 variant increases relative genetic predisposition to late-onset Alzheimer's disease, but it is not a diagnosis and does not guarantee the disease: a large share of carriers never show clinical signs. This is sensitive information, and many people choose to discuss the decision to take this specific test with a doctor or genetic counselor beforehand.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
How does a genetic test for biological age differ from cognitive testing or aging biomarker analysis?
Cognitive testing and laboratory analysis of biomarkers, such as oxidative stress, show the actual state here and now. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. Cognitive testing shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
How reliable is a genetic assessment of markers related to biological aging?

The reliability of a genetic assessment of markers related to biological aging depends on two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic test for biological age diagnose dementia or Parkinson's disease?
No, the test does not establish diagnoses and does not rule out conditions, including dementia, Parkinson's disease or osteoporosis. If you have symptoms, see the relevant doctor: only they can carry out diagnosis and treatment.
What should I do after receiving the report?
Discuss significant results with your doctor or a genetic counselor, especially for markers related to cognitive aging. Do not change your lifestyle or a supplement regimen based on the genetic report alone.
Contact us arrow_outward

Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.