







IMPORTANT!
THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.
The Apixmed Prism Men's Health genetic test covers 34 markers across six areas of reproductive and hormonal health, including 22 complex markers and 12 individual genetic variants in 9 genes.
A DNA kit for collecting your saliva sample yourself is already included in the price of the test.
Genotyping of the sample in an accredited laboratory.
A report explaining 34 markers and genetic variants in plain language, with an interpretation of the results:
22 polygenic (complex) traits with an explanation of your individual result and what it means;
12 individual genetic variants with an explanation of their possible biological significance;
Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.
Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.
The option of a consultation with an Apixmed Prism specialist based on your report results.
Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.
Data protection in line with ISO 27001, GDPR and HIPAA standards.
The Men's Health genetic test covers six areas, within which it analyzes 22 complex markers and 12 individual genetic variants in 9 genes: from fertility and sexual function to prostate health, androgen status and cancer conditions. The test presents results in two groups: complex markers are calculated polygenically and describe a relative shift in population-level risk, while individual genetic variants with mechanistic links are interpreted individually. Among the latter are variants in the BRCA2 and CHEK2 genes that carry substantially greater clinical weight — they are not a diagnosis and require confirmation by clinical sequencing. The test does not measure any marker directly — instead it examines the stable genetic context that complements a urological examination and laboratory tests rather than replacing them.
DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.
22 markers across six areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.
Male fertility and sperm quality: testicular disease
Sexual function: erectile dysfunction, sexual dysfunction, sexual activity
Prostate and lower urinary tract health: prostate disease, benign prostatic hyperplasia with lower urinary tract symptoms, prostatitis, chronic prostatitis (chronic pelvic pain syndrome), prostate-specific antigen (PSA)
Hormonal markers and androgen status: luteinising hormone (LH), follicle-stimulating hormone (FSH), testosterone, bioavailable testosterone, oestradiol, DHEA, sex hormone-binding globulin (SHBG), male hypogonadism
Age-related and androgen-dependent male traits: androgenetic alopecia in men, facial and body hair growth, timing of puberty in men
Cancer risks in men's health: prostate cancer, testicular germ cell tumor
12 genetic variants in 9 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.
FSHR: the follicle-stimulating hormone receptor, associated with reproductive hormones
NOS3: associated with erectile function
KLK3: encodes PSA; three variants are associated with baseline PSA levels regardless of prostate status
AR: the androgen receptor, associated with tissue sensitivity to androgens
SPOCK1 and SRD5A2: associated with androgen-dependent traits, including hair growth, three variants
BRCA2: hereditary predisposition to breast and ovarian cancer; in men, relevant to prostate and breast cancer, one variant
MSMB and HOXB13: associated with predisposition to prostate cancer
This is not full sequencing of these genes but an analysis of several specific variants that are well documented in ClinVar. Any positive result for these requires confirmation by clinical sequencing and consultation with a genetic counselor before any medical decisions are made.
Family history of prostate cancer or hereditary breast cancer: specific genetic context for a conversation with a urologist or genetic counselor.
Planning pregnancy with a partner: context on male fertility for a joint conversation with a doctor.
Age 40+ and prostate prevention: specific topics for routine urological examinations.
When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.
The Men's Health test is not a diagnosis and does not replace consultation with a doctor.
The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis and do not confirm or rule out conditions, including cancer. The test does not replace PSA testing, ultrasound, semen analysis or other urological investigations. Clinical decisions are made by a specialist, taking into account your history, symptoms, age, medication and test results.