







IMPORTANT!
THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.
The Apixmed Prism Respiratory System Health genetic test covers 22 markers across four areas of lung and airway function, including 16 complex markers and 6 individual genetic variants in 6 genes.
A DNA kit for collecting your saliva sample yourself is already included in the price of the test.
Genotyping of the sample in an accredited laboratory.
A report explaining 22 markers and genetic variants in plain language, with an interpretation of the results:
16 polygenic (complex) traits with an explanation of your individual result and what it means;
6 individual genetic variants with an explanation of their possible biological significance.
Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.
Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.
The option of a consultation with an Apixmed Prism specialist based on your report results.
Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.
Data protection in line with ISO 27001, GDPR and HIPAA standards.
The Respiratory System Health genetic test covers four areas, within which it analyzes 16 complex markers and 6 individual genetic variants in 6 genes: from lung function to lower and upper airway conditions and sleep-related conditions. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements spirometry and other investigations rather than replacing them.
DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.
16 markers across four areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.
Lung function: forced expiratory volume in one second (FEV₁), forced vital capacity (FVC), FEV₁/FVC ratio, peak expiratory flow
Lower airway conditions: asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, chronic mucus hypersecretion
Upper airways and sinuses: allergic rhinitis, chronic rhinosinusitis, nasal polyps, sinus congestion
Interstitial, infectious and sleep-related respiratory conditions: pneumonia, obstructive sleep apnea, interstitial lung disease, idiopathic pulmonary fibrosis
6 genetic variants in 6 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.
CHRNA3: associated with nicotine dependence and lung function
HHIP and FAM13A: associated with COPD and lung function
GSDMB and IL33: associated with asthma
MUC5B: an airway mucin whose variant is one of the best-studied associations with idiopathic pulmonary fibrosis
Family history of asthma or COPD: specific genetic context for a conversation with a pulmonologist.
Smoking or occupational lung risks: additional context for prevention.
Chronic nose and sinus symptoms: specific topics for a conversation with an ENT specialist.
When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.
The Respiratory System Health test is not a diagnosis and does not replace consultation with a doctor.
The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace spirometry, X-rays or other respiratory investigations. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.