







IMPORTANT!
THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.
The Apixmed Prism Thyroid, Adrenal and Parathyroid genetic test covers 39 markers across four areas of endocrine gland function, including 25 complex markers and 14 individual genetic variants in 15 genes.
A DNA kit for collecting your saliva sample yourself is already included in the price of the test.
Genotyping of the sample in an accredited laboratory.
A report explaining 39 markers and genetic variants in plain language, with an interpretation of the results:
25 polygenic (complex) traits with an explanation of your individual result and what it means;
14 individual genetic variants with an explanation of their possible biological significance.
Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.
Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.
The option of a consultation with an Apixmed Prism specialist based on your report results.
Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.
Data protection in line with ISO 27001, GDPR and HIPAA standards.
The Thyroid, Adrenal and Parathyroid genetic test covers four areas, within which it analyzes 25 complex markers and 14 individual genetic variants in 15 genes: from thyroid function to adrenal hormones and calcium metabolism. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements laboratory hormone tests rather than replacing them.
DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.
25 markers across four areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.
Hormones and quantitative thyroid function: thyroid-stimulating hormone (TSH), free thyroxine (T4), free triiodothyronine (T3), free T3-to-free T4 ratio
Thyroid disease: thyroid disease (general marker), hypothyroidism, hyperthyroidism, thyroiditis, autoimmune thyroid disease, Hashimoto's thyroiditis, Graves' disease, goiter, thyroid nodules, thyroid cancer
Adrenal hormones and the stress response: morning cortisol, dehydroepiandrosterone sulfate (DHEA-S), aldosterone, renin or renin activity, Addison's disease
Parathyroid glands, calcium and phosphate: parathyroid hormone (PTH), serum calcium, serum phosphate, bone mineral density, hyperparathyroidism, hypoparathyroidism
14 genetic variants in 15 genes and loci. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.
PDE8B: associated with TSH levels
DIO1 and DIO2: conversion of thyroid hormones, associated with free T3 and free T4 levels
CTLA4 and PTPN22: associated with autoimmune thyroid conditions
TSHR: the TSH receptor, associated with Graves' disease
FOXE1: associated with thyroid function
NKX2-1/PTCSC3: a locus whose variant is associated with predisposition to thyroid cancer
SERPINA6 and HSD11B1: associated with cortisol levels
NR3C1: the cortisol receptor
CYP11B2: associated with aldosterone levels
CASR: the calcium-sensing receptor, associated with calcium levels
CYP24A1: the vitamin D pathway, associated with bone mineral density
Family history of thyroid disease: specific genetic context for a conversation with an endocrinologist.
Chronic fatigue or stress: additional context on cortisol, without determining the cause of symptoms on your own.
Interest in preventing autoimmune conditions: specific topics for laboratory monitoring instead of guesswork.
When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.
The Thyroid, Adrenal and Parathyroid DNA Test is not a diagnosis and does not replace consultation with a doctor.
The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace laboratory hormone tests or a thyroid ultrasound. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.