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Thyroid, Adrenal and Parathyroid | DNA Test
Illustration of a thyroid gland on a blue background with a green “with DNA kit” badge — the Thyroid, Adrenal and Parathyroid genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Thyroid, Adrenal and Parathyroid genetic test: Hormones and quantitative thyroid function, Thyroid disease, Adrenal hormones and the stress response, Parathyroid glands, calcium and phosphate — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 25 complex traits, 14 individual genetic variants — the Thyroid, Adrenal and Parathyroid genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of a thyroid gland on a blue background with a green “with DNA kit” badge — the Thyroid, Adrenal and Parathyroid genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Thyroid, Adrenal and Parathyroid genetic test: Hormones and quantitative thyroid function, Thyroid disease, Adrenal hormones and the stress response, Parathyroid glands, calcium and phosphate — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 25 complex traits, 14 individual genetic variants — the Thyroid, Adrenal and Parathyroid genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Thyroid, Adrenal and Parathyroid | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT!

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Thyroid, Adrenal and Parathyroid genetic test covers 39 markers across four areas of endocrine gland function, including 25 complex markers and 14 individual genetic variants in 15 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 39 markers and genetic variants in plain language, with an interpretation of the results:

    • 25 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 14 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Thyroid, Adrenal and Parathyroid genetic test covers four areas, within which it analyzes 25 complex markers and 14 individual genetic variants in 15 genes: from thyroid function to adrenal hormones and calcium metabolism. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements laboratory hormone tests rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

25 markers across four areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Hormones and quantitative thyroid function: thyroid-stimulating hormone (TSH), free thyroxine (T4), free triiodothyronine (T3), free T3-to-free T4 ratio

  • Thyroid disease: thyroid disease (general marker), hypothyroidism, hyperthyroidism, thyroiditis, autoimmune thyroid disease, Hashimoto's thyroiditis, Graves' disease, goiter, thyroid nodules, thyroid cancer

  • Adrenal hormones and the stress response: morning cortisol, dehydroepiandrosterone sulfate (DHEA-S), aldosterone, renin or renin activity, Addison's disease

  • Parathyroid glands, calcium and phosphate: parathyroid hormone (PTH), serum calcium, serum phosphate, bone mineral density, hyperparathyroidism, hypoparathyroidism

Individual genetic variants with mechanistic links

14 genetic variants in 15 genes and loci. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • PDE8B: associated with TSH levels

  • DIO1 and DIO2: conversion of thyroid hormones, associated with free T3 and free T4 levels

  • CTLA4 and PTPN22: associated with autoimmune thyroid conditions

  • TSHR: the TSH receptor, associated with Graves' disease

  • FOXE1: associated with thyroid function

  • NKX2-1/PTCSC3: a locus whose variant is associated with predisposition to thyroid cancer

  • SERPINA6 and HSD11B1: associated with cortisol levels

  • NR3C1: the cortisol receptor

  • CYP11B2: associated with aldosterone levels

  • CASR: the calcium-sensing receptor, associated with calcium levels

  • CYP24A1: the vitamin D pathway, associated with bone mineral density

Who the Apixmed Prism Thyroid, Adrenal and Parathyroid DNA Test is for

  • Family history of thyroid disease: specific genetic context for a conversation with an endocrinologist.

  • Chronic fatigue or stress: additional context on cortisol, without determining the cause of symptoms on your own.

  • Interest in preventing autoimmune conditions: specific topics for laboratory monitoring instead of guesswork.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Thyroid, Adrenal and Parathyroid DNA Test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace laboratory hormone tests or a thyroid ultrasound. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.

Frequently Asked Questions

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How does a genetic thyroid test differ from a hormone panel?
A blood test for TSH, free T3 and free T4 shows hormone levels here and now, and they are affected by health status, medication and the time of collection. A genetic test does not measure those levels: it describes statistical associations between DNA variants and markers established in population studies. A thyroid hormone panel shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Does an elevated genetic predisposition to thyroid cancer mean I will definitely develop it?
No. The test analyzes polygenic associations, not variants of hereditary cancer syndromes. An elevated genetic predisposition is not a prognosis of disease: decisions about screening and next steps are made by a doctor.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
What does the TSHR variant mean?
The TSHR gene encodes the thyroid-stimulating hormone receptor and is associated with Graves' disease, an autoimmune condition linked to hyperthyroidism. On its own, the variant does not establish a diagnosis and does not indicate a specific hormone level: that requires laboratory tests and an endocrinologist's examination.
How reliable is a genetic thyroid test?

The reliability of a genetic thyroid test has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic thyroid test diagnose a thyroid condition?
No, the test does not establish diagnoses and does not rule out conditions, including hypothyroidism, hyperthyroidism or Hashimoto's thyroiditis. If you have symptoms or abnormal laboratory results, see an endocrinologist: only they can carry out diagnosis and treatment.
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Any questions left?

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