







IMPORTANT!
THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.
The Apixmed Prism Eye and Ear Health genetic test covers 42 markers across seven areas of vision and hearing, including 35 complex markers and 7 individual genetic variants in 6 genes.
A DNA kit for collecting your saliva sample yourself is already included in the price of the test.
Genotyping of the sample in an accredited laboratory.
A report explaining 42 markers and genetic variants in plain language, with an interpretation of the results:
35 polygenic (complex) traits with an explanation of your individual result and what it means;
7 individual genetic variants with an explanation of their possible biological significance.
Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.
Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.
The option of a consultation with an Apixmed Prism specialist based on your report results.
Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.
Data protection in line with ISO 27001, GDPR and HIPAA standards.
The Eye and Ear Health genetic test covers seven areas, within which it analyzes 35 complex markers and 7 individual genetic variants in 6 genes: from refraction and intraocular pressure to the state of the retina, visual function and hearing. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements ophthalmological and ENT examinations rather than replacing them.
DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.
35 markers across seven areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.
Refraction and eye shape: refractive error, nearsightedness, farsightedness, astigmatism, corneal astigmatism, axial eye length
Anterior segment and intraocular pressure: intraocular pressure, glaucoma, central corneal thickness, corneal hysteresis, keratoconus, cataracts, conjunctivitis, dry eye disease, eye inflammation, uveitis
Retina and optic nerve: age-related macular degeneration (AMD), diabetic retinopathy, retinal nerve fiber layer thickness, ganglion cell and inner plexiform layer thickness, retinal vessel caliber, retinal vessel fractal density
Visual function and other eye conditions: eye disease, visual acuity, contrast sensitivity, pseudoexfoliation syndrome, exfoliative glaucoma
Hearing and auditory function: hearing loss, age-related hearing decline in adulthood, difficulty hearing in background noise
Inner ear and balance disorders: tinnitus, vertigo (benign paroxysmal positional vertigo, BPPV), Ménière's disease
Middle and outer ear: middle ear disease (otitis media), otosclerosis
7 genetic variants in 6 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.
SIX6: associated with glaucoma and intraocular pressure
LOXL1: associated with exfoliative glaucoma, two variants
CFH, ARMS2 and HTRA1: variants of these genes are among the best-studied associations with age-related macular degeneration
ABCC11: associated with earwax type, dry or wet
Family history of glaucoma or macular degeneration: specific genetic context for a conversation with an ophthalmologist.
Age 50+ and vision prevention: specific topics for routine eye examinations.
Gradual hearing decline: additional context for a conversation with an ENT specialist.
When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.
The Eye and Ear Health test is not a diagnosis and does not replace consultation with a doctor.
The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The test does not replace an eye examination, intraocular pressure measurement, a dilated fundus exam or audiometry. Clinical decisions are made by a specialist, taking into account your history, symptoms, age, medication and test results.