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Prices About us How does it work Laboratory Contacts
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Apixmed Prism — an innovative next-generation genetic analytics platform
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Sleep and Circadian Rhythms | DNA Test
Illustration of an alarm clock on a blue background with a green “with DNA kit” badge — the Sleep and Circadian Rhythms genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Sleep and Circadian Rhythms genetic test: Sleep duration and timing, Sleep quality and architecture, Sleep continuity and fragmentation, Sleep disturbances, Circadian features and daytime sleep — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 18 complex traits, 8 individual genetic variants — the Sleep and Circadian Rhythms genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of an alarm clock on a blue background with a green “with DNA kit” badge — the Sleep and Circadian Rhythms genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Sleep and Circadian Rhythms genetic test: Sleep duration and timing, Sleep quality and architecture, Sleep continuity and fragmentation, Sleep disturbances, Circadian features and daytime sleep — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 18 complex traits, 8 individual genetic variants — the Sleep and Circadian Rhythms genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Sleep and Circadian Rhythms | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT! 

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Sleep and Circadian Rhythms genetic test covers 26 markers across five areas of sleep and circadian regulation, including 18 complex markers and 8 individual genetic variants in 5 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 26 markers and genetic variants in plain language, with an interpretation of the results:

    • 18 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 8 individual genetic variants with an explanation of their possible biological significance.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Sleep and Circadian Rhythms genetic test covers five areas, within which it analyzes 18 complex markers and 8 individual genetic variants in 5 genes: from sleep duration and architecture to chronotype, caffeine sensitivity and sleep disturbances. It assesses how your genetic profile and individual genetic variants are associated with a relatively higher or lower predisposition for each marker compared with a reference population. The test does not measure any marker directly — instead it examines the stable genetic context that complements polysomnography and other sleep investigations rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

18 markers across five areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Sleep duration and timing: sleep duration

  • Sleep quality and architecture: sleep quality, sleep latency, sleep depth, NREM sleep duration, REM sleep duration

  • Sleep continuity and fragmentation: wake after sleep onset

  • Sleep disturbances: insomnia, obstructive sleep apnea, snoring, restless legs syndrome, movement during sleep, REM sleep behavior disorder, sleepwalking (somnambulism)

  • Circadian features and daytime sleep: chronotype, daytime sleepiness, daytime napping, caffeine-related sleep disturbance

Individual genetic variants with mechanistic links

8 genetic variants in 5 genes and loci. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • ADA: associated with sleep depth

  • ADORA2A: associated with caffeine metabolism and its effect on sleep

  • MEIS1: associated with restless legs syndrome

  • CLOCK: a key circadian rhythm gene

  • RGS16: associated with chronotype, four variants

Who the Apixmed Prism Sleep and Circadian Rhythms DNA Test is for

  • Chronic sleep problems: additional context for a conversation with a sleep specialist.

  • Caffeine sensitivity: genetic context for planning your daily schedule.

  • Shift work or frequent flying: chronotype context for managing your schedule better.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Sleep and Circadian Rhythms test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a sleep disorder and do not determine treatment. The test does not replace polysomnography or consultation with a sleep specialist. Clinical decisions are made by a specialist, taking into account your history, symptoms, age, medication and test results.

Frequently Asked Questions

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How does a genetic sleep test differ from polysomnography?
Polysomnography, a laboratory sleep study, shows the actual structure of your sleep on a particular night. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. Polysomnography shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both studies together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Will a genetic sleep test show how many hours of sleep I need?
No. The test shows a genetic predisposition to a relatively longer or shorter sleep duration compared with the population, not a specific recommended number of hours for you personally. Optimal sleep duration is best determined by how you feel and, if needed, a consultation with a sleep specialist.
How do complex markers differ from individual polymorphisms?
These are two different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented by name, with their own interpretation, and are not included in the complex markers. This is an additional layer for those who want to see specific variants, not grounds for drawing conclusions from any one of them.
How reliable is a genetic sleep test?

The reliability of a genetic sleep test has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic sleep test be used to diagnose insomnia or sleep apnea?
No, the test does not establish diagnoses and does not rule out conditions, including insomnia or obstructive sleep apnea. If you have symptoms, see a sleep specialist: only they can carry out diagnosis and treatment.
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Any questions left?

Leave your contact details — our specialists will contact you shortly. We will help you understand the offers, select a test according to your request, and answer any questions about the product and process.