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Prices About us How does it work Laboratory Contacts
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Apixmed Prism — an innovative next-generation genetic analytics platform
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Women's Health | DNA Test
Illustration of a female symbol on a blue background with a green “with DNA kit” badge — the Women's Health genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Women's Health genetic test: Reproductive period and ovarian aging, Menstrual cycle and bleeding, Ovarian conditions and endocrine disorders, Fertility and ovarian reserve, Uterine, cervical and pelvic health, Pregnancy complications, Hormonal markers of women's health, Predisposition to breast cancer and gynecological cancers, Bone health in the context of menopause — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 40 complex traits, 31 individual genetic variants — the Women's Health genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.
Illustration of a female symbol on a blue background with a green “with DNA kit” badge — the Women's Health genetic test by Apixmed Prism, the sample-collection-kit variant.Tablet mockup with the Apixmed PRISM logo and a list of report categories for the Women's Health genetic test: Reproductive period and ovarian aging, Menstrual cycle and bleeding, Ovarian conditions and endocrine disorders, Fertility and ovarian reserve, Uterine, cervical and pelvic health, Pregnancy complications, Hormonal markers of women's health, Predisposition to breast cancer and gynecological cancers, Bone health in the context of menopause — on a blue background.Infographic with a DNA helix on a blue background and a stats card: 700,000 genetic markers, 40 complex traits, 31 individual genetic variants — the Women's Health genetic test by Apixmed Prism.Open box of the Apixmed Prism DNA saliva collection kit on a blue background, with captions describing the test's benefits: collect your sample at home, personalized lifestyle recommendations, secure data storage.

Women's Health | DNA Test

12 500 UAH
9 999 UAH

IMPORTANT! 

THE PRICE OF THE TEST INCLUDES A DNA SAMPLE COLLECTION KIT.

About the test

The Apixmed Prism Women's Health genetic test covers 71 markers across nine areas of reproductive and hormonal health, including 40 complex markers and 31 individual genetic variants in 28 genes.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the test.

  • Genotyping of the sample in an accredited laboratory.

  • A report explaining 71 markers and genetic variants in plain language, with an interpretation of the results:

    • 40 polygenic (complex) traits with an explanation of your individual result and what it means;

    • 31 individual genetic variants with an explanation of their possible biological significance;

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • The option of a consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Women's Health genetic test covers nine areas, within which it analyzes 40 complex markers and 31 individual genetic variants in 28 genes: from the reproductive period and hormonal profile to uterine health, pregnancy complications and cancers of the female reproductive system. The test presents results in two groups: complex markers are calculated polygenically and describe a relative shift in population-level risk, while individual genetic variants with mechanistic links are interpreted individually. Among the latter are variants in the BRCA1, BRCA2 and CHEK2 genes that carry substantially greater clinical weight — they are not a diagnosis and require confirmation by clinical sequencing. The test does not measure any marker directly — instead it examines the stable genetic context that complements gynecological examination and laboratory tests rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the genetic test covers

Complex markers (PRS method)

40 markers across nine areas. Assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition, and no single one of them determines the picture on its own.

  • Reproductive period and ovarian aging: age at menarche, age at natural menopause, ovarian insufficiency, vasomotor menopause symptoms

  • Menstrual cycle and bleeding: menstrual cycle length, heavy menstrual bleeding

  • Ovarian conditions and endocrine disorders: polycystic ovary syndrome (PCOS), ovarian cyst, ovarian dysfunction

  • Fertility and ovarian reserve: female infertility, time to pregnancy (fecundability), anti-Müllerian hormone (AMH)

  • Uterine, cervical and pelvic health: uterine disease, endometriosis, uterine fibroids, pelvic organ prolapse, HPV-associated cervical changes

  • Pregnancy complications: gestational diabetes, preeclampsia, gestational thrombocytopenia, preterm birth, postpartum depression

  • Hormonal markers of women's health: follicle-stimulating hormone (FSH), luteinising hormone (LH), oestradiol, progesterone, testosterone, bioavailable testosterone, DHEA, pregnenolone, sex hormone-binding globulin (SHBG), oestrogen metabolism

  • Predisposition to breast cancer and gynecological cancers: mammographic breast density, breast cancer, ovarian cancer, endometrial cancer, cervical cancer

  • Bone health in the context of menopause: bone mineral density, osteoporosis, fractures

Individual genetic variants with mechanistic links

31 genetic variants in 28 genes. A mechanistic link to the trait is described for each, so they are interpreted individually and are not included in the complex markers.

  • LIN28B: associated with age at menarche

  • MCM8, BRSK1 and HELB: associated with menopause and ovarian reserve

  • FSHB, FSHR, LHCGR, DENND1A and THADA: associated with reproductive hormones and polycystic ovary syndrome (PCOS)

  • WNT4 and GREB1: associated with endometriosis

  • BET1L and TNRC6B: associated with uterine fibroids

  • TERT: telomere length and telomerase activity

  • TCF7L2: associated with gestational diabetes

  • FLT1: associated with preeclampsia

  • F5 and F2: clotting factors; the Leiden and G20210A variants are associated with thrombophilia, including in the context of pregnancy

  • CYP19A1, COMT, CYP1B1 and ESR1: associated with estrogen metabolism and sensitivity

  • BRCA1 and BRCA2: hereditary predisposition to breast and ovarian cancer, three variants

  • CHEK2: hereditary predisposition to breast cancer, two variants, including I157T

  • FGFR2, TOX3 and BNC2: polygenic associations with breast and ovarian cancer

This is not full sequencing of these genes but an analysis of several specific variants that are well documented in ClinVar. Any positive result for these requires confirmation by clinical sequencing and consultation with a genetic counselor before any medical decisions are made.

Who the Apixmed Prism Women's Health DNA Test is for

  • Planning pregnancy: context on thrombophilia and pregnancy complications for a conversation with an obstetrician-gynecologist.

  • Family history of breast or ovarian cancer: specific genetic context for a conversation with a genetic counselor.

  • Approaching menopause: additional context on hormonal profile and bone health.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Women's Health test is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis and do not confirm or rule out conditions, including cancer. The test does not replace a gynecological exam, ultrasound, hormone tests or recommended screening programs. Clinical decisions are made by a specialist, taking into account your history, symptoms, age, medication and test results.

Frequently Asked Questions

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How does a genetic test for women differ from a gynecological exam?
A gynecological exam, ultrasound and hormone tests show the state of the reproductive system here and now. A genetic test does not show that state: it describes statistical associations between DNA variants and markers established in population studies. A gynecological exam shows the state of your body right now; a DNA test shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
Does a positive result for BRCA1, BRCA2 or CHEK2 mean I will definitely get cancer?
No. These variants increase genetic predisposition to breast and ovarian cancer, but they are not a diagnosis and do not guarantee the disease. The test analyzes several specific known variants, not the entire sequence of the BRCA1, BRCA2 and CHEK2 genes, so any positive result must be confirmed by clinical sequencing and a consultation with a genetic counselor before deciding on further monitoring.
How do complex markers differ from individual polymorphisms and pathogenic variants?
These are three different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented individually, with their own interpretation, and are not included in the complex markers. Pathogenic variants in the BRCA1, BRCA2 and CHEK2 genes stand apart: their individual effect on risk is substantially greater and established in clinical research. The report keeps these categories separate so their weight is not mixed together.
Does carrying F5 or F2 mean my pregnancy will definitely be complicated?
No. The F5 (Leiden) and F2 (G20210A) variants increase relative genetic predisposition to thrombosis, including in pregnancy, but most carriers carry a pregnancy to term without complications. Decisions about additional monitoring or prevention are made by an obstetrician-gynecologist, taking into account the full clinical picture.
Will the test show my estradiol or testosterone level?
No. Your actual level of any hormone is shown by a laboratory blood test. The genetic report only describes which DNA variants are associated with this marker in population studies, and does not claim that your specific level is elevated or low.
How reliable is a genetic test for women?

The reliability of a genetic test for women has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. The report states the level of evidence for each marker separately.

Can a genetic test for women establish a diagnosis?
No, the test does not establish diagnoses and does not rule out conditions, including endometriosis, PCOS or cancer. If you have symptoms or abnormal laboratory results, see a doctor: only they can carry out diagnosis and treatment.
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