





IMPORTANT!
THE PRICE OF THE PANEL INCLUDES A DNA SAMPLE COLLECTION KIT.
The Apixmed Prism Ultima DNA panel brings together all Apixmed Prism areas in one study: over 1,000 markers and polymorphisms across 25 areas, including more than 760 complex markers and more than 280 individual polymorphisms.
A DNA kit for collecting your saliva sample yourself is already included in the price of the panel.
Genotyping of the sample in an accredited laboratory.
25 individual topic reports combined into one study from a single genetic file:
more than 760 polygenic (complex) traits with an explanation of your individual result and what it means;
more than 280 individual genetic variants with an explanation of their possible biological significance;
pathogenic variants in genes linked to hereditary cancer syndromes — presented as separate sections in the relevant reports.
Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.
Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.
A consultation with an Apixmed Prism specialist based on your report results.
Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.
Data protection in line with ISO 27001, GDPR and HIPAA standards.
The Ultima DNA panel covers 25 areas, within which it analyzes more than 760 complex markers and more than 280 individual polymorphisms. The Apixmed Prism product line has 26 topic areas in total, but Ultima shows exactly the 25 that are relevant to you personally: women's and men's health are analyzed as separate areas, and only one of the two applies to any given person. It assesses how your genetic profile and individual polymorphisms are associated with a relatively higher or lower predisposition for each marker compared with a reference population. Genetic analysis does not measure any marker directly — instead it examines the stable genetic context that complements laboratory tests, examinations and consultation with a specialist rather than replacing them.
DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.
For each area, the number of complex markers and individual polymorphisms is listed. Complex markers are assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition. Individual polymorphisms are interpreted individually and are not included in the complex markers. The full list is provided in the separate report for each area within Ultima.
Vitamins and Micronutrients — 31 complex markers and 21 polymorphisms: fat- and water-soluble vitamins, carotenoids, electrolytes, macrominerals, iron status, trace elements. Key genes: MTHFR, VDR, HFE.
Amino Acids — 39 complex markers and 7 polymorphisms: branched-chain amino acids (BCAA), essential and non-essential amino acids, the urea cycle, one-carbon metabolism, creatine and muscle metabolism. Key genes: MTHFR, CPS1.
Blood Biomarkers — 46 complex markers and 8 polymorphisms: red blood cell indices, white blood cell profile, platelets and coagulation, iron status, liver markers, inflammation markers. Key genes: F5, F2, HFE.
Lipids, Cholesterol and Fatty Acids — 33 complex markers and 17 polymorphisms: omega-3 and omega-6 fatty acids, the cholesterol and triglyceride profile, apolipoproteins, lipid metabolism disorders. Key genes: APOE, PCSK9, LPA.
Cardiovascular Health — 39 complex markers and 7 polymorphisms: blood pressure, cardiac conduction, vascular stiffness and atherosclerosis, cardiomyopathies, coronary disease, cerebrovascular events. Key genes: APOE, AGT.
Glucose and Metabolic Syndrome — 37 complex markers and 14 polymorphisms: glycemic biomarkers, insulin secretion and action, body composition, adipokines, appetite regulation, diabetic complications. Key genes: TCF7L2, MC4R.
Liver, Gallbladder and Pancreas — 30 complex markers and 9 polymorphisms: liver enzymes, metabolic and inflammatory liver disease, fibrosis, gallbladder conditions, pancreatic function. Key genes: PNPLA3, TM6SF2.
Digestive System Health and Microbiome — 23 complex markers and 5 polymorphisms: the esophagus and reflux conditions, the stomach, bowel motility, inflammatory bowel disease, the microbiome and gut barrier. Key genes: MCM6, NOD2.
Kidneys and Urinary Tract — 22 complex markers and 6 polymorphisms: filtration and nitrogen metabolism, electrolytes and urate, glomerular conditions, urinary tract disease. Key gene: UMOD.
Thyroid, Adrenal and Parathyroid Glands — 28 complex markers and 14 polymorphisms: thyroid hormones and disease, adrenal hormones, parathyroid glands, calcium and phosphate. Key locus: NKX2-1/PTCSC3.
Reproductive, Growth and Metabolic Hormones — 29 complex markers and 16 polymorphisms: sex and reproductive hormones, pituitary function and the growth axis, pancreatic endocrine function, appetite hormones. Key gene: FTO.
Women's Health — 40 complex markers and 33 polymorphisms: the reproductive period, the menstrual cycle, fertility, pregnancy complications, hormonal markers, predisposition to breast cancer. Key genes: BRCA1, BRCA2, CHEK2.
Men's Health — 24 complex markers and 13 polymorphisms: fertility, sexual function, prostate health, androgen status. Key genes: BRCA2, CHEK2, KLK3.
Cancer Risks — 38 complex markers and 20 polymorphisms: cancers of the skin, genitourinary system, digestive tract and respiratory system, hematologic malignancies, CNS and eye tumors. Key genes: BRCA1, BRCA2, MUTYH, APC.
Allergies and Intolerances — 17 complex markers and 11 polymorphisms: general allergic predisposition, respiratory allergies, food intolerances, skin and contact allergies. Key gene: MCM6.
Immunity, Infections and Autoimmune Conditions — 45 complex markers and 18 polymorphisms: systemic and organ-specific autoimmune conditions, inflammatory bowel disease, bacterial and viral infections, immune biomarkers. Key genes: NOD2, PSCA.
Respiratory System Health — 16 complex markers and 6 polymorphisms: lung function, lower airway conditions, upper airways and sinuses, sleep-related respiratory conditions. Key genes: MUC5B, CHRNA3.
Mental Health and Personality — 39 complex markers and 1 polymorphism: affective and psychotic conditions, anxiety and traumatic stress, personality traits, creativity, psychological well-being. Key gene: BDNF.
Sleep and Circadian Rhythms — 18 complex markers and 10 polymorphisms: sleep duration and timing, sleep quality and architecture, sleep continuity, sleep disturbances, circadian features. Key genes: CLOCK, CYP1A2.
Addictions and Behavior — 25 complex markers and 6 polymorphisms: alcohol consumption, smoking and nicotine behavior, risk-taking behavior, macronutrient intake, chemosensory perception. Key genes: ALDH2, ADH1B, TAS2R38.
Eye and Ear Health — 35 complex markers and 7 polymorphisms: refraction and eye shape, intraocular pressure, the retina and optic nerve, hearing and auditory function, the inner ear. Key genes: CFH, ARMS2.
Dental and Oral Health — 35 complex markers and 7 polymorphisms: tooth development, cavities and enamel, gums and periodontium, jaw and bite, oral cancers. Key genes: TAS2R38, IL1A.
Skin, Hair and Appearance — 36 complex markers and 16 polymorphisms: skin structure and aging, barrier and sensitivity, pigmentation and sun response, acne, hair growth and loss. Key genes: MC1R, HERC2/OCA2.
Musculoskeletal System, Injury and Recovery — 22 complex markers and 15 polymorphisms: muscle mass and function, bone density, joint health, the spine, tendons and ligaments. Key genes: COL1A1, GDF5.
Athletic Potential and Physical Performance — 20 complex markers and 12 polymorphisms: aerobic capacity and recovery, strength and body composition, exercise biomarkers, physical activity patterns. Key genes: ACTN3, ACE.
Longevity and Biological Aging — 35 complex markers and 20 polymorphisms: healthspan, molecular and cellular aging, physical vulnerability, brain aging, sensory aging, bone aging. Key genes: APOE, FOXO3, TERT.
Women's and men's health are two separate areas, and only one of them applies to any given person. That is why Ultima includes 25 of the 26 areas.
In the Cancer Risks, Women's Health and Men's Health areas, pathogenic variants of the BRCA1, BRCA2, CHEK2, APC and MUTYH genes are presented as a separate section. These variants carry substantially greater clinical weight than the polygenic associations.
This is not full sequencing of these genes but an analysis of several specific variants that are well documented in ClinVar. Any positive result for these requires confirmation by clinical sequencing and consultation with a genetic counselor before any medical decisions are made.
A comprehensive approach to prevention: one genetic file and a complete map across 25 areas instead of several separate reports.
Family history of several different conditions: specific genetic context for a conversation with the relevant specialist in each area.
Long-term health planning: a single data set that can be reinterpreted for years without repeat testing.
When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.
The Ultima DNA Panel is not a diagnosis and does not replace consultation with a doctor.
The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The panel does not replace laboratory tests, imaging or other clinical investigations in any of the 25 areas. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.