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Ultima Genetic Panel
Ілюстрація «перлина» на синьому тлі із зеленою позначкою «з ДНК набором» — генетична панель «Ultima» від Apixmed Prism, варіант із набором для забору зразка ДНК.Infographic with a DNA helix on a blue background and a statistics card: 700K genetic markers, 1000+ indicators and predispositions, 25 health directions — Ultima DNA test by Apixmed Prism.Розкрита коробка набору для збору слини на аналіз ДНК Apixmed Prism на синьому тлі, поруч підписи про переваги тесту: збір зразка вдома, персональні рекомендації щодо способу життя, безпечне зберігання даних.
Ілюстрація «перлина» на синьому тлі із зеленою позначкою «з ДНК набором» — генетична панель «Ultima» від Apixmed Prism, варіант із набором для забору зразка ДНК.Infographic with a DNA helix on a blue background and a statistics card: 700K genetic markers, 1000+ indicators and predispositions, 25 health directions — Ultima DNA test by Apixmed Prism.Розкрита коробка набору для збору слини на аналіз ДНК Apixmed Prism на синьому тлі, поруч підписи про переваги тесту: збір зразка вдома, персональні рекомендації щодо способу життя, безпечне зберігання даних.

Ultima Genetic Panel

50 000 UAH
29 999 UAH

IMPORTANT!

THE PRICE OF THE PANEL INCLUDES A DNA SAMPLE COLLECTION KIT.

About the panel

The Apixmed Prism Ultima DNA panel brings together all Apixmed Prism areas in one study: over 1,000 markers and polymorphisms across 25 areas, including more than 760 complex markers and more than 280 individual polymorphisms.

What you get from the report

  • A DNA kit for collecting your saliva sample yourself is already included in the price of the panel.

  • Genotyping of the sample in an accredited laboratory.

  • 25 individual topic reports combined into one study from a single genetic file:

    • more than 760 polygenic (complex) traits with an explanation of your individual result and what it means;

    • more than 280 individual genetic variants with an explanation of their possible biological significance;

    • pathogenic variants in genes linked to hereditary cancer syndromes — presented as separate sections in the relevant reports.

  • Context for every marker: genetics is not considered in isolation from lifestyle, age, environment and other factors.

  • Personalized recommendations on nutrition, physical activity, sleep, lifestyle and preventive approaches.

  • A consultation with an Apixmed Prism specialist based on your report results.

  • Pointers to potentially relevant laboratory or clinical parameters that you can discuss with your doctor.

  • Data protection in line with ISO 27001, GDPR and HIPAA standards.

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Free delivery across Ukraine
14 days for refund
Certified laboratory in the EU

Description

The Ultima DNA panel covers 25 areas, within which it analyzes more than 760 complex markers and more than 280 individual polymorphisms. The Apixmed Prism product line has 26 topic areas in total, but Ultima shows exactly the 25 that are relevant to you personally: women's and men's health are analyzed as separate areas, and only one of the two applies to any given person. It assesses how your genetic profile and individual polymorphisms are associated with a relatively higher or lower predisposition for each marker compared with a reference population. Genetic analysis does not measure any marker directly — instead it examines the stable genetic context that complements laboratory tests, examinations and consultation with a specialist rather than replacing them.

How the sample is collected

DNA sample collection is done using saliva. You receive the kit by post and collect your own DNA sample into a special tube — it takes just a few minutes and requires no preparation. The sample is then sent for analysis to an accredited laboratory, and you receive your result in digital format.

What the DNA panel covers

Areas included in Ultima

For each area, the number of complex markers and individual polymorphisms is listed. Complex markers are assessed using polygenic risk scores: tens and hundreds of variants together shape the contribution to a predisposition. Individual polymorphisms are interpreted individually and are not included in the complex markers. The full list is provided in the separate report for each area within Ultima.

  • Vitamins and Micronutrients — 31 complex markers and 21 polymorphisms: fat- and water-soluble vitamins, carotenoids, electrolytes, macrominerals, iron status, trace elements. Key genes: MTHFR, VDR, HFE.

  • Amino Acids — 39 complex markers and 7 polymorphisms: branched-chain amino acids (BCAA), essential and non-essential amino acids, the urea cycle, one-carbon metabolism, creatine and muscle metabolism. Key genes: MTHFR, CPS1.

  • Blood Biomarkers — 46 complex markers and 8 polymorphisms: red blood cell indices, white blood cell profile, platelets and coagulation, iron status, liver markers, inflammation markers. Key genes: F5, F2, HFE.

  • Lipids, Cholesterol and Fatty Acids — 33 complex markers and 17 polymorphisms: omega-3 and omega-6 fatty acids, the cholesterol and triglyceride profile, apolipoproteins, lipid metabolism disorders. Key genes: APOE, PCSK9, LPA.

  • Cardiovascular Health — 39 complex markers and 7 polymorphisms: blood pressure, cardiac conduction, vascular stiffness and atherosclerosis, cardiomyopathies, coronary disease, cerebrovascular events. Key genes: APOE, AGT.

  • Glucose and Metabolic Syndrome — 37 complex markers and 14 polymorphisms: glycemic biomarkers, insulin secretion and action, body composition, adipokines, appetite regulation, diabetic complications. Key genes: TCF7L2, MC4R.

  • Liver, Gallbladder and Pancreas — 30 complex markers and 9 polymorphisms: liver enzymes, metabolic and inflammatory liver disease, fibrosis, gallbladder conditions, pancreatic function. Key genes: PNPLA3, TM6SF2.

  • Digestive System Health and Microbiome — 23 complex markers and 5 polymorphisms: the esophagus and reflux conditions, the stomach, bowel motility, inflammatory bowel disease, the microbiome and gut barrier. Key genes: MCM6, NOD2.

  • Kidneys and Urinary Tract — 22 complex markers and 6 polymorphisms: filtration and nitrogen metabolism, electrolytes and urate, glomerular conditions, urinary tract disease. Key gene: UMOD.

  • Thyroid, Adrenal and Parathyroid Glands — 28 complex markers and 14 polymorphisms: thyroid hormones and disease, adrenal hormones, parathyroid glands, calcium and phosphate. Key locus: NKX2-1/PTCSC3.

  • Reproductive, Growth and Metabolic Hormones — 29 complex markers and 16 polymorphisms: sex and reproductive hormones, pituitary function and the growth axis, pancreatic endocrine function, appetite hormones. Key gene: FTO.

  • Women's Health — 40 complex markers and 33 polymorphisms: the reproductive period, the menstrual cycle, fertility, pregnancy complications, hormonal markers, predisposition to breast cancer. Key genes: BRCA1, BRCA2, CHEK2.

  • Men's Health — 24 complex markers and 13 polymorphisms: fertility, sexual function, prostate health, androgen status. Key genes: BRCA2, CHEK2, KLK3.

  • Cancer Risks — 38 complex markers and 20 polymorphisms: cancers of the skin, genitourinary system, digestive tract and respiratory system, hematologic malignancies, CNS and eye tumors. Key genes: BRCA1, BRCA2, MUTYH, APC.

  • Allergies and Intolerances — 17 complex markers and 11 polymorphisms: general allergic predisposition, respiratory allergies, food intolerances, skin and contact allergies. Key gene: MCM6.

  • Immunity, Infections and Autoimmune Conditions — 45 complex markers and 18 polymorphisms: systemic and organ-specific autoimmune conditions, inflammatory bowel disease, bacterial and viral infections, immune biomarkers. Key genes: NOD2, PSCA.

  • Respiratory System Health — 16 complex markers and 6 polymorphisms: lung function, lower airway conditions, upper airways and sinuses, sleep-related respiratory conditions. Key genes: MUC5B, CHRNA3.

  • Mental Health and Personality — 39 complex markers and 1 polymorphism: affective and psychotic conditions, anxiety and traumatic stress, personality traits, creativity, psychological well-being. Key gene: BDNF.

  • Sleep and Circadian Rhythms — 18 complex markers and 10 polymorphisms: sleep duration and timing, sleep quality and architecture, sleep continuity, sleep disturbances, circadian features. Key genes: CLOCK, CYP1A2.

  • Addictions and Behavior — 25 complex markers and 6 polymorphisms: alcohol consumption, smoking and nicotine behavior, risk-taking behavior, macronutrient intake, chemosensory perception. Key genes: ALDH2, ADH1B, TAS2R38.

  • Eye and Ear Health — 35 complex markers and 7 polymorphisms: refraction and eye shape, intraocular pressure, the retina and optic nerve, hearing and auditory function, the inner ear. Key genes: CFH, ARMS2.

  • Dental and Oral Health — 35 complex markers and 7 polymorphisms: tooth development, cavities and enamel, gums and periodontium, jaw and bite, oral cancers. Key genes: TAS2R38, IL1A.

  • Skin, Hair and Appearance — 36 complex markers and 16 polymorphisms: skin structure and aging, barrier and sensitivity, pigmentation and sun response, acne, hair growth and loss. Key genes: MC1R, HERC2/OCA2.

  • Musculoskeletal System, Injury and Recovery — 22 complex markers and 15 polymorphisms: muscle mass and function, bone density, joint health, the spine, tendons and ligaments. Key genes: COL1A1, GDF5.

  • Athletic Potential and Physical Performance — 20 complex markers and 12 polymorphisms: aerobic capacity and recovery, strength and body composition, exercise biomarkers, physical activity patterns. Key genes: ACTN3, ACE.

  • Longevity and Biological Aging — 35 complex markers and 20 polymorphisms: healthspan, molecular and cellular aging, physical vulnerability, brain aging, sensory aging, bone aging. Key genes: APOE, FOXO3, TERT.

Women's and men's health are two separate areas, and only one of them applies to any given person. That is why Ultima includes 25 of the 26 areas.

Pathogenic variants linked to hereditary cancer syndromes

In the Cancer Risks, Women's Health and Men's Health areas, pathogenic variants of the BRCA1, BRCA2, CHEK2, APC and MUTYH genes are presented as a separate section. These variants carry substantially greater clinical weight than the polygenic associations.

This is not full sequencing of these genes but an analysis of several specific variants that are well documented in ClinVar. Any positive result for these requires confirmation by clinical sequencing and consultation with a genetic counselor before any medical decisions are made.

Who the Apixmed Prism Ultima DNA Panel is for

  • A comprehensive approach to prevention: one genetic file and a complete map across 25 areas instead of several separate reports.

  • Family history of several different conditions: specific genetic context for a conversation with the relevant specialist in each area.

  • Long-term health planning: a single data set that can be reinterpreted for years without repeat testing.

  • When choosing supplements: a reason to discuss whether they are appropriate with your doctor, not grounds to change anything on your own.

The Ultima DNA Panel is not a diagnosis and does not replace consultation with a doctor.

The results assess probability rather than establishing a predetermined outcome. They are not a diagnosis, do not confirm a disease and do not determine treatment. The panel does not replace laboratory tests, imaging or other clinical investigations in any of the 25 areas. Clinical decisions are made by a specialist, taking into account your history, symptoms, diet, age, medication and laboratory data.

Поширені запитання

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Why does the complete Ultima genetic panel cover 25 areas if Apixmed Prism has 26?
Women's and men's health are two separate analysis areas, but only one of them applies to any given person. Ultima therefore includes the area that matches your profile, so the total number of areas relevant to you is 25 out of 26.
How is the sample collected?
You receive the DNA kit by post and collect saliva into a special tube yourself — the procedure takes a few minutes and requires no special preparation or clinic visit. The sample is then sent to the laboratory for genotyping, and you receive the result in digital format.
How does Ultima differ from individual Apixmed Prism genetic tests?
Ultima uses the same genetic data as the individual tests, but it brings all relevant areas together in one study from a single genetic file and a single order. This is more convenient and more economical than ordering each area separately if you want the full picture rather than a single specific topic. Ultima also includes a consultation with an Apixmed Prism specialist based on your report results.
How do complex markers differ from individual polymorphisms and pathogenic variants?
These are three different levels of the report. Complex markers are calculated polygenically: tens and hundreds of variants contribute to a predisposition at once, and the assessment takes the contribution of each into account. Individual polymorphisms with mechanistic links are presented individually, with their own interpretation, and are not included in the complex markers. Pathogenic variants in the BRCA1, BRCA2, CHEK2, APC and MUTYH genes stand apart: their individual effect on risk is substantially greater and established in clinical research. The report keeps these categories separate so their weight is not mixed together.
How does a complete genetic panel differ from laboratory tests?
Laboratory and biochemical tests measure specific markers here and now, and they are affected by diet, health status, medication and the time of collection. Genetic analysis does not measure those markers: it describes statistical associations between DNA variants and markers established in population studies. A laboratory test shows the state of your body right now; a DNA panel shows individual features of how it functions and its predispositions, which can help you understand that state better if you read the results of both together rather than each on its own.
Will Ultima show my actual levels of vitamins, hormones or other markers?
No. Your actual level of any marker is shown by a laboratory test. Ultima describes which DNA variants are associated with each marker in population studies, and does not claim that your specific level is elevated or low.
How reliable is the complete Ultima genetic panel?

The reliability of a complete genetic panel has two components. The first is the technical accuracy of genotyping, ensured by the laboratory's accreditation within its official scope. The second is the strength of evidence behind the interpretation, and this is not the same for every marker: some associations have been confirmed in large studies, while others so far rest on preliminary data and may require confirmation. Each of the 25 reports states the level of evidence for each marker separately.

Can this panel establish a diagnosis?
No, the panel does not establish a diagnosis in any of the 25 areas and does not rule out conditions. If you have symptoms or abnormal laboratory results, see the relevant doctor: only they can carry out diagnosis and treatment.
Do I need to take the complete genetic panel again?
No. Your DNA sequence does not change, so the genotyping result remains valid for life. Only the interpretation may be updated: as new research emerges, the reports are re-read against the same data, without a new sample.
What should I do after receiving the Ultima DNA panel reports?
Start with the limitations sections in each report, then discuss significant results with your doctor, a dietitian or a genetic counselor. Do not change treatment, your diet or a supplement regimen based on the genetic report alone.
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